View source for 3tiq


==Crystal structure of Staphylococcus aureus SasG G51-E-G52 module==
<StructureSection load='3tiq' size='340' side='right'caption='[[3tiq]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tiq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TIQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8739&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tiq OCA], [https://pdbe.org/3tiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tiq RCSB], [https://www.ebi.ac.uk/pdbsum/3tiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tiq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SASG_STAA8 SASG_STAA8] Promotes adhesion of bacterial cells to human squamous nasal epithelial cells, a phenomenon which is likely to be important in nasal colonization. Forms short, extremely dense and thin fibrils all over the bacterial surface. Does not bind to either buccal cells or non-differentiated keratinocytes. Promotes cellular aggregation leading to biofilm formation.<ref>PMID:14523109</ref> <ref>PMID:17660408</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
[[Category: Gruszka DT]]
[[Category: Potts JR]]
[[Category: Turkenburg JP]]
[[Category: Wojdyla JA]]