View source for 3tnl


==1.45 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with Shikimate and NAD.==
<StructureSection load='3tnl' size='340' side='right'caption='[[3tnl]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tnl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TNL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tnl OCA], [https://pdbe.org/3tnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tnl RCSB], [https://www.ebi.ac.uk/pdbsum/3tnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tnl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROE_LISMO AROE_LISMO] Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).[HAMAP-Rule:MF_00222]

==See Also==
*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Listeria monocytogenes EGD-e]]
[[Category: Anderson WF]]
[[Category: Halavaty A]]
[[Category: Light SH]]
[[Category: Minasov G]]
[[Category: Papazisi L]]
[[Category: Shuvalova L]]