View source for 3tuf


==Structure of the SpoIIQ-SpoIIIAH pore forming complex.==
<StructureSection load='3tuf' size='340' side='right'caption='[[3tuf]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3tuf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TUF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tuf OCA], [https://pdbe.org/3tuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tuf RCSB], [https://www.ebi.ac.uk/pdbsum/3tuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tuf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SP2Q_BACSU SP2Q_BACSU] Involved in forespore engulfment and required for anchoring membrane proteins on the forespore side of the septal membrane. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling.<ref>PMID:9140963</ref> <ref>PMID:10781563</ref> <ref>PMID:15882622</ref> <ref>PMID:15752199</ref> <ref>PMID:16164552</ref> <ref>PMID:16959571</ref> <ref>PMID:17824930</ref> <ref>PMID:18077456</ref> <ref>PMID:18485064</ref> <ref>PMID:18812514</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Blagova EV]]
[[Category: Levdikov VM]]
[[Category: Wilkinson AJ]]