View source for 3twb


==Crystal structure of gluconate dehydratase (TARGET EFI-501679) from Salmonella enterica subsp. enterica serovar Enteritidis str. P125109 complexed with magnesium and gluconic acid==
<StructureSection load='3twb' size='340' side='right'caption='[[3twb]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3twb]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Enteritidis_str._P125109 Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TWB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3twb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3twb OCA], [https://pdbe.org/3twb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3twb RCSB], [https://www.ebi.ac.uk/pdbsum/3twb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3twb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DGD_SALEP DGD_SALEP] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Enteritidis str. P125109]]
[[Category: Almo SC]]
[[Category: Bhosle R]]
[[Category: Chowdhury S]]
[[Category: Evans B]]
[[Category: Gerlt JA]]
[[Category: Hammonds J]]
[[Category: Hillerich B]]
[[Category: Imker HJ]]
[[Category: Patskovsky Y]]
[[Category: Scott Glenn A]]
[[Category: Seidel RD]]
[[Category: Toro R]]
[[Category: Washington E]]
[[Category: Zencheck WD]]