View source for 3u59


==N-terminal 98-aa fragment of smooth muscle tropomyosin beta==
<StructureSection load='3u59' size='340' side='right'caption='[[3u59]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3u59]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U59 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u59 OCA], [https://pdbe.org/3u59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u59 RCSB], [https://www.ebi.ac.uk/pdbsum/3u59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u59 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPM2_CHICK TPM2_CHICK] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

==See Also==
*[[Tropomyosin 3D structures|Tropomyosin 3D structures]]
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Dominguez R]]
[[Category: Jampani N]]