View source for 3udu


==Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni==
<StructureSection load='3udu' size='340' side='right'caption='[[3udu]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3udu]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni Campylobacter jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UDU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3udu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3udu OCA], [https://pdbe.org/3udu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3udu RCSB], [https://www.ebi.ac.uk/pdbsum/3udu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3udu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEU3_CAMJE LEU3_CAMJE] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.

==See Also==
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
__TOC__
</StructureSection>
[[Category: Campylobacter jejuni]]
[[Category: Large Structures]]
[[Category: Anderson WF]]
[[Category: Chruszcz M]]
[[Category: Grimshaw S]]
[[Category: Minor W]]
[[Category: Onopriyenko O]]
[[Category: Savchenko A]]
[[Category: Tkaczuk KL]]