View source for 3uo2


==Jac1 co-chaperone from Saccharomyces cerevisiae==
<StructureSection load='3uo2' size='340' side='right'caption='[[3uo2]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3uo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UO2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo2 OCA], [https://pdbe.org/3uo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uo2 RCSB], [https://www.ebi.ac.uk/pdbsum/3uo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/JAC1_YEAST JAC1_YEAST] Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of its specialized Hsp70 chaperone partner SSQ1. Binds to the substrate protein ISU1 and targets it to SSQ1. May function together with SSQ1 in the dislocation of the Fe/S cluster from ISU1 and its insertion into apoproteins.<ref>PMID:11171977</ref> <ref>PMID:9813017</ref> <ref>PMID:11278728</ref> <ref>PMID:11273703</ref> <ref>PMID:12970193</ref> <ref>PMID:12756240</ref> <ref>PMID:15123690</ref> <ref>PMID:16431909</ref> <ref>PMID:16551614</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Bigelow L]]
[[Category: Craig EA]]
[[Category: Dutkiewicz R]]
[[Category: Joachimiak A]]
[[Category: Marszalek J]]
[[Category: Mulligan R]]
[[Category: Osipiuk J]]