View source for 3uvj


==Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.==
<StructureSection load='3uvj' size='340' side='right'caption='[[3uvj]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3uvj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UVJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uvj OCA], [https://pdbe.org/3uvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uvj RCSB], [https://www.ebi.ac.uk/pdbsum/3uvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uvj ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/GCYA1_HUMAN GCYA1_HUMAN] Moyamoya disease with early-onset achalasia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/GCYA1_HUMAN GCYA1_HUMAN] 

==See Also==
*[[Guanylate cyclase 3D structures|Guanylate cyclase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Allerston CK]]
[[Category: Arrowsmith CH]]
[[Category: Berridge G]]
[[Category: Bountra C]]
[[Category: Chalk R]]
[[Category: Cooper CDO]]
[[Category: Edwards A]]
[[Category: Gileadi O]]
[[Category: Savitsky P]]
[[Category: Vollmar M]]
[[Category: Weigelt J]]
[[Category: Von Delft F]]