View source for 3vmz


==Crystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channel (oxidation/H2O2)==
<StructureSection load='3vmz' size='340' side='right'caption='[[3vmz]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vmz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vmz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vmz OCA], [https://pdbe.org/3vmz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vmz RCSB], [https://www.ebi.ac.uk/pdbsum/3vmz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vmz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HVCN1_MOUSE HVCN1_MOUSE] Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis (By similarity).

==See Also==
*[[Ion channels 3D structures|Ion channels 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Fujiwara Y]]
[[Category: Kobayashi M]]
[[Category: Nakagawa A]]
[[Category: Okamura Y]]
[[Category: Takeshita K]]