View source for 3wkv


==Voltage-gated proton channel: VSOP/Hv1 chimeric channel==
<StructureSection load='3wkv' size='340' side='right'caption='[[3wkv]], [[Resolution|resolution]] 3.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3wkv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WKV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.453&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wkv OCA], [https://pdbe.org/3wkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wkv RCSB], [https://www.ebi.ac.uk/pdbsum/3wkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wkv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HVCN1_MOUSE HVCN1_MOUSE] Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis (By similarity).

==See Also==
*[[Ion channels 3D structures|Ion channels 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Fujiwara Y]]
[[Category: Kawanabe A]]
[[Category: Kurokawa T]]
[[Category: Matsuda M]]
[[Category: Nakagawa A]]
[[Category: Narita H]]
[[Category: Okamura Y]]
[[Category: Okochi Y]]
[[Category: Sakata S]]
[[Category: Takeshita K]]
[[Category: Yamashita E]]