View source for 3zsc


==Catalytic function and substrate recognition of the pectate lyase from Thermotoga maritima==
<StructureSection load='3zsc' size='340' side='right'caption='[[3zsc]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3zsc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZSC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZSC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADA:ALPHA-D-GALACTOPYRANURONIC+ACID'>ADA</scene>, <scene name='pdbligand=AQA:4-DEOXY-BETA-L-THREO-HEX-4-ENOPYRANURONIC+ACID'>AQA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zsc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zsc OCA], [https://pdbe.org/3zsc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zsc RCSB], [https://www.ebi.ac.uk/pdbsum/3zsc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zsc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PTLY_THEMA PTLY_THEMA] Cleaves unsaturated trigalacturonate from pectin. Activity is highest towards polygalacturonic acid, activity on methylated pectins decreases with an increasing degree of methylation.<ref>PMID:12443532</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima]]
[[Category: Bjornvad M]]
[[Category: Frisner H]]
[[Category: Hotchkiss A]]
[[Category: Johansen KS]]
[[Category: Larsen S]]
[[Category: McDonough MA]]
[[Category: Sonksen C]]
[[Category: Thymark M]]