View source for 3zzd


==Crystal structure of 3C protease mutant (T68A and N126Y) of coxsackievirus B3 complexed with alpha, beta-unsaturated ethyl ester inhibitor 85==
<StructureSection load='3zzd' size='340' side='right'caption='[[3zzd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3zzd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_B3 Coxsackievirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZZD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G85:N-[(BENZYLOXY)CARBONYL]-O-TERT-BUTYL-L-SERYL-N-{(2R)-5-ETHOXY-5-OXO-1-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTAN-2-YL}-L-PHENYLALANINAMIDE'>G85</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zzd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zzd OCA], [https://pdbe.org/3zzd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zzd RCSB], [https://www.ebi.ac.uk/pdbsum/3zzd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zzd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5UEA2_9ENTO Q5UEA2_9ENTO] 

==See Also==
*[[Proteinase 3D structures|Proteinase 3D structures]]
*[[Virus protease 3D structures|Virus protease 3D structures]]
__TOC__
</StructureSection>
[[Category: Coxsackievirus B3]]
[[Category: Large Structures]]
[[Category: Anand K]]
[[Category: Hilgenfeld R]]
[[Category: Mesters JR]]
[[Category: Tan J]]