View source for 43fx


==DPR epimerase complex, quabodepistat-bound state==
<StructureSection load='43fx' size='340' side='right'caption='[[43fx]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[43fx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=43FX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=43FX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.69&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L5L:5-[[(3~{R},4~{R})-1-[4-chloranyl-2,6-bis(fluoranyl)phenyl]-3,4-bis(oxidanyl)piperidin-4-yl]methoxy]-8-fluoranyl-3,4-dihydro-1~{H}-quinolin-2-one'>A1L5L</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=43fx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=43fx OCA], [https://pdbe.org/43fx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=43fx RCSB], [https://www.ebi.ac.uk/pdbsum/43fx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=43fx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPRE1_MYCTU DPRE1_MYCTU] Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (DPR) to yield decaprenylphosphoryl 2-keto-ribose (DPX).<ref>PMID:16291675</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Gao S]]
[[Category: Wu F]]
[[Category: Zhang L]]