View source for 4bqf


==Arabidopsis thaliana cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with acarbose==
<StructureSection load='4bqf' size='340' side='right'caption='[[4bqf]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4bqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BQF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PRD_900022:beta-acarbose'>PRD_900022</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqf OCA], [https://pdbe.org/4bqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bqf RCSB], [https://www.ebi.ac.uk/pdbsum/4bqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bqf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PHS2_ARATH PHS2_ARATH] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity).
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Bornemann S]]
[[Category: Field RA]]
[[Category: Gunning AP]]
[[Category: Hetru AC]]
[[Category: Lawson DM]]
[[Category: Nepogodiev SA]]
[[Category: O'Neill EC]]
[[Category: Rashid AM]]
[[Category: Rejzek M]]
[[Category: Stevenson CEM]]