View source for 4bsr


==Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form==
<StructureSection load='4bsr' size='340' side='right'caption='[[4bsr]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4bsr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BSR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bsr OCA], [https://pdbe.org/4bsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bsr RCSB], [https://www.ebi.ac.uk/pdbsum/4bsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bsr ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/LGR5_HUMAN LGR5_HUMAN]] Orphan receptor. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Clevers H]]
[[Category: Forneris F]]
[[Category: Granneman JCM]]
[[Category: Gros P]]
[[Category: Huch M]]
[[Category: Peng WC]]
[[Category: De Lau W]]