View source for 4ckx


==Structure of the Mycobacterium tuberculosis Type II Dehydroquinase N12S mutant (Crystal Form 2)==
<StructureSection load='4ckx' size='340' side='right'caption='[[4ckx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ckx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckx OCA], [https://pdbe.org/4ckx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckx RCSB], [https://www.ebi.ac.uk/pdbsum/4ckx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]

==See Also==
*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Gonzalez-Bello C]]
[[Category: Hawkins AR]]
[[Category: Lamb H]]
[[Category: Llamas-Saiz AL]]
[[Category: Maneiro M]]
[[Category: Otero JM]]
[[Category: Peon A]]
[[Category: Sedes A]]
[[Category: Van Raaij MJ]]