View source for 4dbb


==The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region==
<StructureSection load='4dbb' size='340' side='right'caption='[[4dbb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dbb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DBB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.901&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dbb OCA], [https://pdbe.org/4dbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dbb RCSB], [https://www.ebi.ac.uk/pdbsum/4dbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dbb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/APBA1_RAT APBA1_RAT] Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-AAP.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Ho A]]
[[Category: Rizo J]]
[[Category: Tomchick DR]]
[[Category: Xu Y]]