View source for 4ddp


==crystal structure of Beclin 1 evolutionarily conserved domain(ECD)==
<StructureSection load='4ddp' size='340' side='right'caption='[[4ddp]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ddp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DDP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.547&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ddp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddp OCA], [https://pdbe.org/4ddp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ddp RCSB], [https://www.ebi.ac.uk/pdbsum/4ddp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ddp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BECN1_HUMAN BECN1_HUMAN] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.<ref>PMID:20208530</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Choi WY]]
[[Category: Huang WJ]]
[[Category: Shi YG]]
[[Category: Wang JW]]