View source for 4dhi


==Structure of C. elegans OTUB1 bound to human UBC13==
<StructureSection load='4dhi' size='340' side='right'caption='[[4dhi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dhi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DHI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dhi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dhi OCA], [https://pdbe.org/4dhi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dhi RCSB], [https://www.ebi.ac.uk/pdbsum/4dhi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dhi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/OTUBL_CAEEL OTUBL_CAEEL] Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Specifically cleaves 'Lys-48'-linked polyubiquitin.<ref>PMID:19211026</ref> 

==See Also==
*[[Thioesterase 3D structures|Thioesterase 3D structures]]
*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Wang T]]
[[Category: Wiener R]]
[[Category: Wolberger C]]
[[Category: Zhang X]]