View source for 4ef6


==Crystal Structure of Mycobacterium tuberculosis Pantothenate synthetase in complex with fragment 1==
<StructureSection load='4ef6' size='340' side='right'caption='[[4ef6]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ef6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EF6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I2E:3-(1,3-BENZODIOXOL-5-YL)PROPANOIC+ACID'>I2E</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ef6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ef6 OCA], [https://pdbe.org/4ef6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ef6 RCSB], [https://www.ebi.ac.uk/pdbsum/4ef6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ef6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> 

==See Also==
*[[Pantothenate synthetase|Pantothenate synthetase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Abell C]]
[[Category: Blundell T]]
[[Category: Ciulli A]]
[[Category: Silvestre HL]]