View source for 4frv


==Crystal structure of mutated cyclophilin B that causes hyperelastosis cutis in the American Quarter Horse==
<StructureSection load='4frv' size='340' side='right'caption='[[4frv]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4frv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FRV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ME2:1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE'>ME2</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4frv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4frv OCA], [https://pdbe.org/4frv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4frv RCSB], [https://www.ebi.ac.uk/pdbsum/4frv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4frv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5YBL8_HORSE A5YBL8_HORSE] PPIases accelerate the folding of proteins.[RuleBase:RU000493]  PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223]

==See Also==
*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
__TOC__
</StructureSection>
[[Category: Equus caballus]]
[[Category: Large Structures]]
[[Category: Bachinger HP]]
[[Category: Boudko SP]]
[[Category: Ishikawa Y]]