View source for 4fuk


==Aminopeptidase from Trypanosoma brucei==
<StructureSection load='4fuk' size='340' side='right'caption='[[4fuk]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fuk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FUK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fuk OCA], [https://pdbe.org/4fuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fuk RCSB], [https://www.ebi.ac.uk/pdbsum/4fuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fuk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4FKC0_TRYB2 Q4FKC0_TRYB2] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) (By similarity).[HAMAP-Rule:MF_03174]

==See Also==
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei brucei TREU927]]
[[Category: Arrowsmith CH]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: El Bakkouri M]]
[[Category: Graslund S]]
[[Category: Hui R]]
[[Category: Lin YH]]
[[Category: Loppnau P]]
[[Category: Osman KT]]
[[Category: Tempel W]]