View source for 4fxy


==Crystal structure of rat neurolysin with bound pyrazolidin inhibitor==
<StructureSection load='4fxy' size='340' side='right'caption='[[4fxy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fxy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FXY FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0W2:1-{(2S)-1-[(3R)-3-(2-CHLOROPHENYL)-2-(2-FLUOROPHENYL)PYRAZOLIDIN-1-YL]-1-OXOPROPAN-2-YL}-3-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]UREA'>0W2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fxy OCA], [https://pdbe.org/4fxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fxy RCSB], [https://www.ebi.ac.uk/pdbsum/4fxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fxy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NEUL_RAT NEUL_RAT] Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A.
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</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Hines CS]]
[[Category: Rodgers DW]]