View source for 4g55


==Clathrin terminal domain complexed with pitstop 2==
<StructureSection load='4g55' size='340' side='right'caption='[[4g55]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4g55]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2xzh 2xzh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G55 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=VH2:N-[5-[(4-BROMOPHENYL)METHYL]-4-HYDROXY-1,3-THIAZOL-2-YL]NAPHTHALENE-1-SULFONAMIDE'>VH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g55 OCA], [https://pdbe.org/4g55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g55 RCSB], [https://www.ebi.ac.uk/pdbsum/4g55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g55 ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN] Translocation renal cell carcinoma;Inflammatory myofibroblastic tumor. 
== Function ==
[https://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

==See Also==
*[[Clathrin 3D structures|Clathrin 3D structures]]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bulut H]]
[[Category: Haucke V]]
[[Category: Saenger W]]
[[Category: Von Kleist L]]