View source for 4geq


==Crystal structure of the Spc24-Spc25/Cnn1 binding interface==
<StructureSection load='4geq' size='340' side='right'caption='[[4geq]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4geq]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GEQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4geq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4geq OCA], [https://pdbe.org/4geq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4geq RCSB], [https://www.ebi.ac.uk/pdbsum/4geq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4geq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPC25_YEAST SPC25_YEAST] Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.<ref>PMID:11266451</ref> <ref>PMID:12514103</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Clausen T]]
[[Category: Heuck A]]
[[Category: Litos G]]
[[Category: Malvezzi F]]
[[Category: Schleiffer A]]
[[Category: Westermann S]]