View source for 4gh4


==Crystal Structure of Foot and Mouth Disease Virus A22 Serotype==
<StructureSection load='4gh4' size='340' side='right'caption='[[4gh4]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gh4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_A Foot-and-mouth disease virus A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GH4 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gh4 OCA], [https://pdbe.org/4gh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gh4 RCSB], [https://www.ebi.ac.uk/pdbsum/4gh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gh4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q6PN23_9PICO Q6PN23_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]

==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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</StructureSection>
[[Category: Foot-and-mouth disease virus A]]
[[Category: Large Structures]]
[[Category: Curry S]]
[[Category: Fry E]]
[[Category: Jinshan R]]
[[Category: Kotecha A]]
[[Category: Stuart D]]