View source for 4gjh


==Crystal Structure of the TRAF domain of TRAF5==
<StructureSection load='4gjh' size='340' side='right'caption='[[4gjh]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gjh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GJH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.805&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjh OCA], [https://pdbe.org/4gjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gjh RCSB], [https://www.ebi.ac.uk/pdbsum/4gjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gjh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRAF5_MOUSE TRAF5_MOUSE] Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.<ref>PMID:15121867</ref> 

==See Also==
*[[TNF receptor-associated factor 3D structures|TNF receptor-associated factor 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Aliyari R]]
[[Category: Cheng D]]
[[Category: Cheng G]]
[[Category: Liang H]]
[[Category: Liu Y]]
[[Category: Reichardt A]]
[[Category: Wang Y]]
[[Category: Zhang P]]