View source for 4gvp


==Crystal Structure of the Response Regulator Protein VraR from Staphylococcus aureus==
<StructureSection load='4gvp' size='340' side='right'caption='[[4gvp]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gvp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GVP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvp OCA], [https://pdbe.org/4gvp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gvp RCSB], [https://www.ebi.ac.uk/pdbsum/4gvp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gvp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VRAR_STAAM VRAR_STAAM] Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. VraR is overexpressed in strain Mu50, which leads to vancomycin resistance.

==See Also==
*[[Response regulator 3D structure|Response regulator 3D structure]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus subsp. aureus Mu50]]
[[Category: Leonard PG]]
[[Category: Stock AM]]