View source for 4gxd


==Crystal structure of D48V mutant of human GLTP bound with 12:0 disulfatide==
<StructureSection load='4gxd' size='340' side='right'caption='[[4gxd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gxd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GXD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0SG:N-{(2S,3R,4E)-1-[(3,6-DI-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]-3-HYDROXYOCTADEC-4-EN-2-YL}DODECANAMIDE'>0SG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gxd OCA], [https://pdbe.org/4gxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gxd RCSB], [https://www.ebi.ac.uk/pdbsum/4gxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gxd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Malinina L]]
[[Category: Ochoa-Lizarralde B]]
[[Category: Popov AN]]
[[Category: Samygina VR]]