View source for 4gzc


==Crystal structure of yeast Ent2 ENTH domain==
<StructureSection load='4gzc' size='340' side='right'caption='[[4gzc]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4gzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GZC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gzc OCA], [https://pdbe.org/4gzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gzc RCSB], [https://www.ebi.ac.uk/pdbsum/4gzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gzc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENT2_YEAST ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.<ref>PMID:10449404</ref> 

==See Also==
*[[Epsin|Epsin]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Costakes GT]]
[[Category: Stauffacher CV]]