View source for 4he6


==Crystal structure of the C-terminal domain of Geobacillus thermoleovorans putative U32 peptidase==
<StructureSection load='4he6' size='340' side='right'caption='[[4he6]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4he6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_thermoleovorans_CCB_US3_UF5 Geobacillus thermoleovorans CCB_US3_UF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HE6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4he6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4he6 OCA], [https://pdbe.org/4he6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4he6 RCSB], [https://www.ebi.ac.uk/pdbsum/4he6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4he6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/G8N3E1_GEOTH G8N3E1_GEOTH] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
While small organic molecules generally crystallize forming tightly packed lattices with little solvent content, proteins form air-sensitive high-solvent-content crystals. Here, the crystallization and full structure analysis of a novel recombinant 10 kDa protein corresponding to the C-terminal domain of a putative U32 peptidase are reported. The orthorhombic crystal contained only 24.5% solvent and is therefore among the most tightly packed protein lattices ever reported.

Ultratight crystal packing of a 10 kDa protein.,Trillo-Muyo S, Jasilionis A, Domagalski MJ, Chruszcz M, Minor W, Kuisiene N, Arolas JL, Sola M, Gomis-Ruth FX Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):464-70. doi:, 10.1107/S0907444912050135. Epub 2013 Feb 16. PMID:23519421<ref>PMID:23519421</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4he6" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Geobacillus thermoleovorans CCB_US3_UF5]]
[[Category: Large Structures]]
[[Category: Arolas JL]]
[[Category: Chruszcz M]]
[[Category: Domagalski MJ]]
[[Category: Gomis-Ruth FX]]
[[Category: Jasilionis A]]
[[Category: Kuisiene N]]
[[Category: Minor W]]
[[Category: Sola M]]
[[Category: Trillo-Muyo S]]