View source for 4hnl


==Crystal structure of ENOLASE EGBG_01401 (TARGET EFI-502226) from Enterococcus gallinarum EG2==
<StructureSection load='4hnl' size='340' side='right'caption='[[4hnl]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hnl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_gallinarum_EG2 Enterococcus gallinarum EG2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HNL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hnl OCA], [https://pdbe.org/4hnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hnl RCSB], [https://www.ebi.ac.uk/pdbsum/4hnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hnl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IMND1_ENTGE IMND1_ENTGE] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> 

==See Also==
*[[Enolase 3D structures|Enolase 3D structures]]
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Enterococcus gallinarum EG2]]
[[Category: Large Structures]]
[[Category: Al Obaidi NF]]
[[Category: Almo SC]]
[[Category: Bhosle R]]
[[Category: Chowdhury S]]
[[Category: Evans B]]
[[Category: Gerlt JA]]
[[Category: Hammonds J]]
[[Category: Hillerich B]]
[[Category: Imker HJ]]
[[Category: Love J]]
[[Category: Patskovsky Y]]
[[Category: Scott Glenn A]]
[[Category: Seidel RD]]
[[Category: Stead M]]
[[Category: Toro R]]
[[Category: Washington E]]
[[Category: Zencheck WD]]