View source for 4hnw


==The NatA Acetyltransferase Complex Bound To Inositol Hexakisphosphate==
<StructureSection load='4hnw' size='340' side='right'caption='[[4hnw]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hnw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HNW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hnw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hnw OCA], [https://pdbe.org/4hnw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hnw RCSB], [https://www.ebi.ac.uk/pdbsum/4hnw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hnw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAT1_YEAST NAT1_YEAST] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome and may present the N termini of nascent polypeptides for acetylation.<ref>PMID:1600941</ref> <ref>PMID:14517307</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Dollins DE]]
[[Category: Endo-Streeter ST]]
[[Category: Immormino RM]]
[[Category: Neubauer JL]]
[[Category: Pemble IV CW]]
[[Category: York JD]]