View source for 4hpw


==Crystal structure of Tyrosine-tRNA ligase mutant complexed with unnatural amino acid 3-o-methyl-Tyrosine==
<StructureSection load='4hpw' size='340' side='right'caption='[[4hpw]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hpw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HPW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.998&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3YM:3-METHOXY-L-TYROSINE'>3YM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hpw OCA], [https://pdbe.org/4hpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hpw RCSB], [https://www.ebi.ac.uk/pdbsum/4hpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hpw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYY_METJA SYY_METJA] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref> 

==See Also==
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii DSM 2661]]
[[Category: Dong J]]
[[Category: Gao F]]
[[Category: Gong W]]
[[Category: Li H]]
[[Category: Li J]]
[[Category: Lu Y]]
[[Category: Mukherjee A]]
[[Category: Nilges M]]
[[Category: Ouyang H]]
[[Category: Wang J]]
[[Category: Xiaoxuan L]]
[[Category: Yu Y]]
[[Category: Zhou Q]]