View source for 4hsb


==S. pombe 3-methyladenine DNA glycosylase-like protein Mag2 bound to damaged DNA==
<StructureSection load='4hsb' size='340' side='right'caption='[[4hsb]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hsb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HSB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hsb OCA], [https://pdbe.org/4hsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hsb RCSB], [https://www.ebi.ac.uk/pdbsum/4hsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hsb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MAG2_SCHPO MAG2_SCHPO] Invlved in base excision repair of methyl methanesulfonate-damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.<ref>PMID:18270439</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Adhikary S]]
[[Category: Eichman BF]]