View source for 4i0j


==SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors==
<StructureSection load='4i0j' size='340' side='right'caption='[[4i0j]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4i0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0J FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=842:N-[(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-({1-[3-(1H-PYRAZOL-1-YL)PHENYL]CYCLOHEXYL}AMINO)PROPYL]ACETAMIDE'>842</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0j OCA], [https://pdbe.org/4i0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0j RCSB], [https://www.ebi.ac.uk/pdbsum/4i0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0j ProSAT]</span></td></tr>
</table>

==See Also==
*[[Beta secretase 3D structures|Beta secretase 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Brecht E]]
[[Category: Yao N]]