View source for 4i92


==Structure of the BSK8 kinase domain==
<StructureSection load='4i92' size='340' side='right'caption='[[4i92]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4i92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I92 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i92 OCA], [https://pdbe.org/4i92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i92 RCSB], [https://www.ebi.ac.uk/pdbsum/4i92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i92 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BSK8_ARATH BSK8_ARATH] Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK4, BSK6 and BSK7 (PubMed:23496207). Involved in the regulation of sucrose-phosphate synthase 1 (SPS1) in the context of sucrose resuply after starvation. Activates BSL2, a phosphatase that may dephosphorylate SPS1, leading to the activation of SPS1 (PubMed:24924143).<ref>PMID:23496207</ref> <ref>PMID:24924143</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Gruetter C]]
[[Category: Rauh D]]