View source for 4icv


==Ubiquitin-like domain of human tubulin folding cofactor E - crystal form B==
<StructureSection load='4icv' size='340' side='right'caption='[[4icv]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4icv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ICV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ICV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PR:PRASEODYMIUM+ION'>PR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4icv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4icv OCA], [https://pdbe.org/4icv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4icv RCSB], [https://www.ebi.ac.uk/pdbsum/4icv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4icv ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/TBCE_HUMAN TBCE_HUMAN] Sanjad-Sakati syndrome;Autosomal recessive Kenny-Caffey syndrome. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TBCE_HUMAN TBCE_HUMAN] Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicated in the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation.<ref>PMID:11847227</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Boutin M]]
[[Category: Coll M]]
[[Category: Janowski R]]
[[Category: Zabala JC]]