View source for 4icx


==N-terminal C2 domain of human CEP120==
<StructureSection load='4icx' size='340' side='right'caption='[[4icx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4icx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ICX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ICX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4icx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4icx OCA], [https://pdbe.org/4icx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4icx RCSB], [https://www.ebi.ac.uk/pdbsum/4icx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4icx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CE120_HUMAN CE120_HUMAN] Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Coll M]]
[[Category: Guarin N]]
[[Category: Janowski R]]