View source for 4imc


==Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase==
<StructureSection load='4imc' size='340' side='right'caption='[[4imc]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4imc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pasteurella_multocida_subsp._gallicida_P1059 Pasteurella multocida subsp. gallicida P1059]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IMC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4imc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4imc OCA], [https://pdbe.org/4imc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4imc RCSB], [https://www.ebi.ac.uk/pdbsum/4imc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4imc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NANA_PASMU NANA_PASMU] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate (By similarity).

==See Also==
*[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pasteurella multocida subsp. gallicida P1059]]
[[Category: Fisher AJ]]
[[Category: Huynh N]]