View source for 4j2w


==Crystal Structure of kynurenine 3-monooxygenase (KMO-396Prot-Se)==
<StructureSection load='4j2w' size='340' side='right'caption='[[4j2w]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4j2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2W FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2w OCA], [https://pdbe.org/4j2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2w RCSB], [https://www.ebi.ac.uk/pdbsum/4j2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KMO_YEAST KMO_YEAST] Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.<ref>PMID:12062417</ref> <ref>PMID:15806102</ref> 

==See Also==
*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Amaral M]]
[[Category: Giorgini F]]
[[Category: Heyes DJ]]
[[Category: Lafite P]]
[[Category: Levy C]]
[[Category: Leys D]]
[[Category: Outeiro TF]]
[[Category: Scrutton NS]]