View source for 4jhs


==Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1==
<StructureSection load='4jhs' size='340' side='right'caption='[[4jhs]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JHS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jhs OCA], [https://pdbe.org/4jhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jhs RCSB], [https://www.ebi.ac.uk/pdbsum/4jhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jhs ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Almo SC]]
[[Category: Bonanno JB]]
[[Category: Celikgil A]]
[[Category: Chan MK]]
[[Category: Garforth S]]
[[Category: Garrett-Thomson SC]]
[[Category: Gizzi A]]
[[Category: Hillerich B]]
[[Category: Lim S]]
[[Category: Matikainen B]]
[[Category: Patel H]]
[[Category: Rand JH]]
[[Category: Seidel R]]
[[Category: Toro R]]