View source for 4jrt


==Crystal structure of an A-form RNA duplex containing three GU base pairs==
<StructureSection load='4jrt' size='340' side='right'caption='[[4jrt]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jrt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JRT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JRT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jrt OCA], [https://pdbe.org/4jrt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jrt RCSB], [https://www.ebi.ac.uk/pdbsum/4jrt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jrt ProSAT]</span></td></tr>
</table>
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== Publication Abstract from PubMed ==
In the course of a crystallographic study of a 132 nt variant of Aquifex aeolicus 6S RNA, a crystal structure of an A-form RNA duplex containing 12 base pairs was solved at a resolution of 2.6 A. In fact, the RNA duplex is part of the 6S RNA and was obtained by accidental but precise degradation of the 6S RNA in a crystallization droplet. 6S RNA degradation was confirmed by microscopic observation of crystals and gel electrophoresis of crystallization droplets. The RNA oligomers obtained form regular A-form duplexes containing three GoU wobble-type base pairs, one of which engages in intermolecular contacts through a ribose-zipper motif at the crystal-packing interface.

Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet.,Kondo J, Dock-Bregeon AC, Willkomm DK, Hartmann RK, Westhof E Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):634-9. doi:, 10.1107/S1744309113013018. Epub 2013 May 24. PMID:23722840<ref>PMID:23722840</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 4jrt" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Dock-Bregeon AC]]
[[Category: Hartmann RK]]
[[Category: Kondo J]]
[[Category: Westhof E]]
[[Category: Willkomm DK]]