View source for 4k42


==Crystal structure of actin in complex with synthetic AplC tail analogue SF01 [(3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate]==
<StructureSection load='4k42' size='340' side='right'caption='[[4k42]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4k42]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K42 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NWM:(3R,4S,5R,6S,10R,11R,12R)-11-(ACETYLOXY)-1-(BENZYLOXY)-14-[FORMYL(METHYL)AMINO]-5-HYDROXY-4,6,10,12-TETRAMETHYL-9-OXOTETRADECAN-3-YL+PROPANOATE'>NWM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k42 OCA], [https://pdbe.org/4k42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k42 RCSB], [https://www.ebi.ac.uk/pdbsum/4k42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k42 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

==See Also==
*[[Actin 3D structures|Actin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Adams PD]]
[[Category: Cecere G]]
[[Category: Fink SJ]]
[[Category: Marriott G]]
[[Category: Moriarty NW]]
[[Category: Paterson I]]
[[Category: Pereira JH]]
[[Category: Petchprayoon C]]