View source for 4k43


==Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]==
<StructureSection load='4k43' size='340' side='right'caption='[[4k43]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4k43]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K43 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PO:N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-DIMETHOXY-11-[(2S,4S,5S)-2-(4-METHOXYPHENYL)-5-METHYL-1,3-DIOXAN-4-YL]-5,9-DIMETHYL-6-OXODODECA-1,7-DIEN-1-YL}-N-METHYLFORMAMIDE'>1PO</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k43 OCA], [https://pdbe.org/4k43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k43 RCSB], [https://www.ebi.ac.uk/pdbsum/4k43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k43 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

==See Also==
*[[Actin 3D structures|Actin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Adams PD]]
[[Category: Cecere G]]
[[Category: Fink SJ]]
[[Category: Marriott G]]
[[Category: Moriarty NW]]
[[Category: Paterson I]]
[[Category: Pereira JH]]
[[Category: Petchprayoon C]]