View source for 4l01


==Crystal structure of the V658F apo Jak1 pseudokinase domain==
<StructureSection load='4l01' size='340' side='right'caption='[[4l01]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4l01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L01 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l01 OCA], [https://pdbe.org/4l01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l01 RCSB], [https://www.ebi.ac.uk/pdbsum/4l01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l01 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

==See Also==
*[[Janus kinase 3D structures|Janus kinase 3D structures]]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Eck MJ]]
[[Category: Rogers JM]]
[[Category: Toms AV]]