View source for 4lcj


==CtBP2 in complex with substrate MTOB==
<StructureSection load='4lcj' size='340' side='right'caption='[[4lcj]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4lcj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LCJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KMT:4-(METHYLSULFANYL)-2-OXOBUTANOIC+ACID'>KMT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lcj OCA], [https://pdbe.org/4lcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lcj RCSB], [https://www.ebi.ac.uk/pdbsum/4lcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lcj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CTBP2_HUMAN CTBP2_HUMAN] Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).  Isoform 2 probably acts as a scaffold for specialized synapses.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hilbert BJ]]
[[Category: Royer Jr WE]]
[[Category: Schiffer CA]]