View source for 4ldu


==Crystal structure of the DNA binding domain of Arabidopsis thaliana auxin response factor 5==
<StructureSection load='4ldu' size='340' side='right'caption='[[4ldu]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ldu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LDU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ldu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ldu OCA], [https://pdbe.org/4ldu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ldu RCSB], [https://www.ebi.ac.uk/pdbsum/4ldu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ldu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARFE_ARATH ARFE_ARATH] Auxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity.<ref>PMID:12036261</ref> <ref>PMID:14973283</ref> <ref>PMID:17553903</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Boer DR]]
[[Category: Coll M]]
[[Category: Freire-Rios A]]
[[Category: Weijers D]]
[[Category: Van den Berg WMA]]