View source for 4mio


==Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD(H) and myo-inositol==
<StructureSection load='4mio' size='340' side='right'caption='[[4mio]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mio]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei_BL23 Lacticaseibacillus casei BL23]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MIO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mio OCA], [https://pdbe.org/4mio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mio RCSB], [https://www.ebi.ac.uk/pdbsum/4mio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mio ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0J9X1Y2_LACCB A0A0J9X1Y2_LACCB] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.[HAMAP-Rule:MF_01671]
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</StructureSection>
[[Category: Lacticaseibacillus casei BL23]]
[[Category: Large Structures]]
[[Category: Bertwistle D]]
[[Category: Palmer DRJ]]
[[Category: Sanders DAR]]