View source for 4mjl


==Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei in complex with NAD and D-chiro-inositol==
<StructureSection load='4mjl' size='340' side='right'caption='[[4mjl]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mjl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lacticaseibacillus_casei_BL23 Lacticaseibacillus casei BL23]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MJL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CBU:(1R,2R,3S,4S,5S,6S)-CYCLOHEXANE-1,2,3,4,5,6-HEXOL'>CBU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mjl OCA], [https://pdbe.org/4mjl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mjl RCSB], [https://www.ebi.ac.uk/pdbsum/4mjl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mjl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0J9X1Y2_LACCB A0A0J9X1Y2_LACCB] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.[HAMAP-Rule:MF_01671]
__TOC__
</StructureSection>
[[Category: Lacticaseibacillus casei BL23]]
[[Category: Large Structures]]
[[Category: Bertwistle D]]
[[Category: Palmer DRJ]]
[[Category: Sanders DAR]]